Isotopically Labeled Compounds
Medchemexpress LLC Nonan-1-ol-d19 | 349553-86-2 | 98.0% | 163.37 | 10 MG
n-Nonyl Alcohol-d19 is the deuterium labeled Nonan-1-ol. It is for research use only. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Pimozide-d4-1 | 2062-78-4 | 100 UG
Pimozide-d4-1 is a deuterium-labeled version of Pimozide, a dopamine receptor antagonist. It exhibits Ki values of 1.4 nM for D2, 2.5 nM for D3, and 588 nM for D1 receptors, along with affinity at the α1-adrenoceptor (Ki of 39 nM). Additionally, Pimozide inhibits STAT3 and STAT5. Deuterium labeling allows for its use as a tracer and internal standard in quantitative analyses, impacting pharmacokinetic and metabolic profiles of drugs.
- Deuterium-labeled compound
- Functions as a dopamine receptor antagonist
- Exhibits affinity at α1-adrenoceptor
- Inhibits STAT3 and STAT5
- Useful as a tracer in drug development
- Serves as an internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
- Impacts pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC 1-Adamantan-d15-amine | 33830-10-3 | MFCD01317436 | 98.0% | 166.34 | C10H2D15N | 10 MG
Amantadine-d15 (1-Adamantanamine-d15) is the deuterium-labeled isotopologue of amantadine supplied as a solid analytical standard for use in mass spectrometry, isotope-dilution quantitation, metabolic, and pharmacokinetic studies. The product is characterized by its molecular formula and verified purity on the certificate of analysis, and is intended for use as an internal standard or tracer in quantitative workflows.
- High isotopic labeling suitable for mass spectrometry applications.
- Purity 98.0% as reported on the certificate of analysis.
- White to off-white solid for convenient storage and handling.
- Appropriate as an internal standard for LC-MS/MS and GC-MS quantitation.
- Provided in a 10 mg quantity for analytical use.
Medchemexpress LLC Candesartan-d4 | 1346604-70-3 | 98.2% | 1 MG
Candesartan-d4 (CV-11974-d4) is the deuterium labeled Candesartan, an orally active angiotensin II AT1-Receptor blocker and PPAR-γ agonist. It has potent and long-lasting antihypertensive effects and is used for the research of hypertension, chronic heart failure (CHF), and traumatic brain injury (TBI).
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes into drug molecules for quantitation during drug development
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Erythromycin-d3 | 959119-26-7 | 95.0% | 1 MG
Erythromycin-d3 is a deuterium-labeled macrolide antibiotic produced by the actinomycete Streptomyces erythreus. It exhibits broad-spectrum antimicrobial activity by binding to bacterial 50S ribosomal subunits, thereby inhibiting RNA-dependent protein synthesis. Beyond its antibiotic properties, Erythromycin also demonstrates antitumor and neuroprotective effects in various research areas.
- Can be utilized as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Taurine-13C2 | 70155-54-3 | MFCD01075566 | 99.9% | 5 MG
Taurine-13C2 is a 13C-labeled form of Taurine, a sulfur-containing amino acid and organic osmolyte. It plays a role in cell volume regulation, serves as a substrate for bile salt formation, and modulates intracellular free calcium concentration. Taurine has also been shown to activate autophagy in adipocytes.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Molecular weight: 127.13
- Isotopic purity: ≥99 atom % 13C
- Assay: ≥98% (CP)
- Mass shift: M+2
- Physical form: solid
- Suitable for bio NMR and mass spectrometry (MS) techniques
- Melting point: >300 °C
Medchemexpress LLC L-cysteine-2,3,3-d3 | 214782-32-8 | MFCD12546019 | 99.2% | 124.18 g/mol | C3H4D3NO2S | 1mg
L-Cysteine-d3 is the deuterium labeled L-Cysteine L-Cysteine is a conditionally essential amino acid which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S) glutathione and taurine L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1]
Cambridge Isotope Laboratories GUANOSINE 5'-TRIPHOSPHATE, AMMONIUM SALT (13C10, 99%; 15N5, 98%) CP >90% (IN SOLN), 100 UMOL
GUANOSINE 5'-TRIPHOSPHATE, AMMONIUM SALT (13C10, 99%; 15N5, 98%) CP >90% (IN SOLN), 100 UMOL
Medchemexpress LLC Decanoic acid-d5 | 1219803-00-5 | 98.3% | 177.30 | C10H15D5O2 | 25 MG
Decanoic acid-d5 is the deuterium-labeled analogue of decanoic (capric) acid provided for research use. It is used as an isotopically labeled standard or tracer in analytical workflows, particularly mass spectrometry and metabolic studies, and is supplied with confirmed chemical and isotopic purity.
- Isotopically labeled (d5) decanoic acid for analytical standards.
- High chemical and isotopic purity for accurate quantitation.
- Available in multiple pre-weighed sizes to suit experimental needs.
- Suitable as an internal standard or tracer in mass spectrometry.
- Provided for research use only; not for human or diagnostic applications.
Cayman Chemical Iloprost-d4 100UG
An internal standard for the quantification of iloprost by GC- or LC-MS
Cambridge Isotope Laboratories ETHYL ACETATE (1-13C, 99%), 5 G, 3424-59-7
ETHYL ACETATE (1-13C, 99%), 5 G, 3424-59-7
Medchemexpress LLC 3-O-methyldopa-d3 hydrate | MFCD11983476 | 232.25 | C10H12D3NO5 | 5 MG
3-O-Methyldopa-d3 hydrate is the deuterium-labeled form of 3-O-methyldopa supplied as a white to off-white solid hydrate. It is designed for use as an internal standard or tracer in quantitative analyses and for research on dopamine metabolism and related neurological disorders.
- Deuterium-labeled internal standard for LC-MS, GC-MS, and NMR.
- Suitable for quantitative tracer and assay development.
- Solid hydrate form with stable isotopic labeling.
- Useful in studies of dopamine metabolism and neurological disease models.
- Supplied in small research-scale quantities for analytical applications.
Medchemexpress LLC Fingolimod-d4 hydrochloride | 1346604-90-7 | 99.0% | 347.96 g/mol | C19H30D4ClNO2 | 5 MG
Fingolimod-d4 hydrochloride is the deuterium-labeled hydrochloride salt of fingolimod provided for research use. It is supplied as a solid with high chemical and isotopic purity, intended as an internal standard or tracer for analytical, pharmacokinetic, and bioanalytical studies. The compound is soluble in DMSO and is stored sealed away from moisture; solvent storage conditions apply.
Cambridge Isotope Laboratories L-LEUCINE-N-T-BOC:H2O (2-13C, 99%), 0.25 G
L-LEUCINE-N-T-BOC:H2O (2-13C, 99%), 0.25 G